Housekeepers handle light cleaning needed for the upkeep of homes as well as commercial buildings, such as offices, hotels, and hospitals. Typically theyll replace bedding, clean rooms, halls and bathrooms, vacuum, sweep, mop, replace toiletries and make beds. Housekeepers handle light cleaning needed for the upkeep of homes as well as commercial buildings, such as offices, hotels, and hospitals. Typically theyll replace bedding, clean rooms, halls and bathrooms, vacuum, sweep, mop, replace toiletries and make beds.